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ESM2 35M Protein Molecular Function

Developed by andrewdalpino
A protein function prediction tool based on the Evolutionary Scale Modeling (ESM), which predicts the molecular function of proteins through amino acid sequences.
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Release Time : 5/12/2025

Model Overview

This model is based on the ESM2 Transformer architecture, pre - trained on UniRef50 and fine - tuned on the AmiGO dataset. It can predict the Gene Ontology (GO) sub - graph of proteins, focusing on molecular function prediction.

Model Features

Accurate prediction
Accurately predict the molecular function of proteins based on the Gene Ontology (GO) and amino acid sequences.
Advanced architecture
Adopt the ESM2 Transformer architecture, which has been pre - trained and fine - tuned to ensure the effectiveness of the model.
Multi - aspect insights
Provide information on the molecular - level functions of proteins, the biological processes they participate in, and their intracellular locations.

Model Capabilities

Protein molecular function prediction
Gene Ontology (GO) sub - graph prediction

Use Cases

Bioinformatics
Protein function annotation
Predict the molecular function of proteins based on amino acid sequences for functional annotation.
Provide the GO term prediction results of proteins.
Protein function research
Help researchers quickly understand the possible functions of unknown proteins.
Provide preliminary predictions of protein functions to guide subsequent experimental design.
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